Changhu Xue Selected Research

Bone Resorption

4/2022	Comparative study of holothurin A and echinoside A on inhibiting the high bone turnover via downregulating PI3K/AKT/β-catenin and OPG/RANKL/NF-κB signaling in ovariectomized mice.
8/2020	The opposite effects of Antarctic krill oil and arachidonic acid-rich oil on bone resorption in ovariectomized mice.
11/2015	Phosphorylated Peptides from Antarctic Krill (Euphausia superba) Prevent Estrogen Deficiency Induced Osteoporosis by Inhibiting Bone Resorption in Ovariectomized Rats.

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Changhu Xue Research Topics

Disease

24	Inflammation (Inflammations) 01/2023 - 10/2014
20	Obesity 03/2023 - 10/2012
17	Insulin Resistance 01/2023 - 10/2012
15	Neoplasms (Cancer) 04/2024 - 04/2005
11	Body Weight (Weight, Body) 04/2024 - 01/2013
11	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 01/2016
11	Osteoporosis 11/2022 - 11/2015
7	Colitis 11/2023 - 11/2019
6	Hyperglycemia 06/2022 - 11/2013
5	Fatty Liver 03/2022 - 05/2012
5	Mucositis 01/2022 - 10/2014
5	Non-alcoholic Fatty Liver Disease 07/2020 - 01/2016
5	Glucose Intolerance 01/2016 - 10/2012
4	Weight Loss (Weight Reduction) 11/2023 - 01/2023
4	Type 2 Diabetes Mellitus (MODY) 08/2023 - 10/2015
4	Atherosclerosis 01/2023 - 01/2018
4	Infections 10/2018 - 02/2010
3	Atrophy 04/2024 - 01/2023
3	Tibial Fractures (Fracture, Tibial) 12/2023 - 03/2017
3	Hepatocellular Carcinoma (Hepatoma) 12/2023 - 01/2023
3	Dysbiosis 01/2023 - 11/2019
3	Bone Resorption 04/2022 - 11/2015
3	Weight Gain 01/2022 - 04/2018
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 05/2024 - 03/2022
2	Lipid Metabolism Disorders (Metabolism Disorders, Lipid) 04/2024 - 04/2024
2	Chronic Disease (Chronic Diseases) 04/2024 - 01/2021
2	Cachexia 04/2024 - 01/2023
2	Fatigue 01/2024 - 01/2017
2	Ulcerative Colitis 09/2023 - 01/2023
2	Cardiovascular Diseases (Cardiovascular Disease) 02/2023 - 01/2018
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023 - 01/2020
2	Neoplasm Metastasis (Metastasis) 11/2022 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2022 - 04/2018
2	Breast Neoplasms (Breast Cancer) 01/2022 - 09/2016
2	Osteoarthritis 08/2021 - 03/2019
2	Neuroinflammatory Diseases 01/2021 - 05/2018

Drug/Important Bio-Agent (IBA)

17	astaxanthine (astaxanthin)IBA 04/2024 - 05/2018
15	LipidsIBA 04/2024 - 05/2012
12	Phospholipids (Phosphatides)FDA LinkGeneric 04/2024 - 07/2013
12	Docosahexaenoic AcidsIBA 11/2023 - 01/2016
11	Eicosapentaenoic AcidIBA 01/2023 - 07/2013
10	Phosphatidylcholines (Phosphatidylcholine)IBA 11/2022 - 01/2016
10	Sucrose (Saccharose)IBA 06/2022 - 07/2014
10	Insulin (Novolin)FDA Link 03/2020 - 10/2012
9	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 10/2012
8	SaponinsIBA 04/2022 - 10/2012
7	fucoidanIBA 05/2024 - 04/2005
7	CytokinesIBA 09/2023 - 03/2011
7	Blood Glucose (Blood Sugar)IBA 08/2023 - 10/2012
7	Proteins (Proteins, Gene)FDA Link 10/2021 - 05/2016
6	CholesterolIBA 04/2024 - 01/2017
6	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 07/2013
5	PlasmalogensIBA 04/2024 - 02/2020
5	Sorafenib (BAY 43-9006)FDA Link 01/2024 - 01/2023
5	Peptides (Polypeptides)IBA 01/2024 - 11/2015
5	SialoglycoproteinsIBA 11/2021 - 02/2016
5	phosphatidylethanolamineIBA 09/2020 - 05/2018
5	Orotic AcidIBA 07/2020 - 05/2012
4	Triglycerides (Triacylglycerol)IBA 04/2024 - 04/2018
4	Dextran SulfateIBA 11/2023 - 11/2019
3	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2020
3	Interleukin-6 (Interleukin 6)IBA 04/2024 - 01/2018
3	Liposomes (Liposome)IBA 02/2023 - 02/2018
3	Ether (Diethyl Ether)IBA 01/2023 - 03/2022
3	neoagarotetraoseIBA 11/2022 - 01/2017
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2022 - 07/2018
3	SphingolipidsIBA 01/2021 - 03/2017
3	phosphatidal ethanolaminesIBA 01/2021 - 05/2018
3	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 08/2020 - 02/2018
3	PrebioticsIBA 07/2020 - 01/2017
3	Messenger RNA (mRNA)IBA 07/2020 - 02/2018
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2020 - 04/2017
3	Polysaccharides (Glycans)IBA 06/2020 - 04/2013
3	InflammasomesIBA 12/2019 - 05/2018
3	fucosylated chondroitin sulfateIBA 03/2019 - 11/2013
3	trimethyloxamine (trimethylamine N-oxide)IBA 12/2018 - 10/2014
3	CerebrosidesIBA 01/2018 - 11/2015
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2017 - 01/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2024 - 12/2023
2	Branched-Chain Amino AcidsIBA 01/2024 - 10/2022
2	Amyloid (Amyloid Fibrils)IBA 11/2023 - 01/2018
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 11/2023 - 09/2023
2	SaltsIBA 11/2023 - 06/2022
2	Dextrans (Dextran)FDA Link 11/2023 - 09/2023
2	EstersIBA 01/2023 - 04/2018
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 11/2022 - 08/2021
2	Phospholipase DIBA 11/2022 - 01/2019
2	CateninsIBA 11/2022 - 04/2016
2	Phospholipid EthersIBA 10/2022 - 08/2021
2	Hematoxylin (Haematoxylon)IBA 06/2022 - 01/2021
2	Bile Acids and Salts (Bile Acids)IBA 06/2022 - 12/2018
2	Eosine Yellowish-(YS) (Eosin)IBA 06/2022 - 01/2021
2	CarrageenanIBA 06/2022 - 11/2021
2	Dietary Fats (Dietary Fat)IBA 01/2022 - 01/2014
2	CurcuminIBA 01/2022 - 05/2021
2	Arachidonic Acid (Vitamin F)IBA 08/2020 - 02/2020

Therapy/Procedure

11	Therapeutics 12/2023 - 04/2014
5	Drug Therapy (Chemotherapy) 01/2022 - 10/2014
3	Ovariectomy (Oophorectomy) 04/2022 - 06/2015
2	Transplantation 01/2024 - 12/2023